| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2016-06-02 |
| タイトル |
|
|
タイトル |
Differentiation of Apical Bud Cells in a Newly Developed Apical Bud Transplantation Model Using GFP Transgenic Mice as Donor. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
apical bud |
| キーワード |
|
|
主題 |
cervical loop |
| キーワード |
|
|
主題 |
歯の移植 |
| キーワード |
|
|
主題 |
齧歯類切歯 |
| キーワード |
|
|
主題 |
上皮間葉転換 |
| キーワード |
|
|
言語 |
en |
|
主題 |
apical bud |
| キーワード |
|
|
言語 |
en |
|
主題 |
cervical loop |
| キーワード |
|
|
言語 |
en |
|
主題 |
tooth transplantation |
| キーワード |
|
|
言語 |
en |
|
主題 |
rodent incisor |
| キーワード |
|
|
言語 |
en |
|
主題 |
epithelial‐mesenchymal transition |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_db06 |
|
資源タイプ |
doctoral thesis |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Maruo, Naoki
Sakagami, Ryuji
Yoshinaga, Yasunori
Okamura, Kazuhiko
Sawa, Yoshihiko
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Rodent mandibular incisors have a unique anatomical structure that allows teeth to grow throughout the lifetime of the rodent. This report presents a novel transplantation technique for studying the apical bud differentiation of rodent mandibular incisors. Incisal apical end tissue with green fluorescent protein from transgenic mouse was transplanted to wild type mice, and the development of the transplanted cells were immunohistologically observed for 12 weeks after the transplantation. Results indicate that the green fluorescent apical end tissue replaced the original tissue, and cells from the apical bud differentiated and extended toward the incisal edge direction. The immunostaining with podoplanin also showed that the characteristics of the green fluorescent tissue were identical to those of the original. The green fluorescent cells were only found in the labial side of the incisor up to 4 weeks. After 12 weeks, however, they were also found in the lingual side. Here the green fluorescent cementocyte-like cells were only present in the cementum close to the dentin surface. This study suggests that some of the cells that form the cellular cementum come from the apical tissue including the apical bud in rodent incisors. |
| 学位名 |
|
|
学位名 |
博士（歯学） |
| 学位授与大学 |
|
|
|
学位授与機関識別子 |
37114 |
|
|
学位授与機関名 |
福岡歯科大学 |
| 学位授与年度 |
|
|
内容記述 |
2015年度 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2016-03-12 |
| 報告番号 |
|
|
学位授与番号 |
甲第278号 |
| 情報源 |
|
|
|
関連名称 |
PLoS One. 2016 Mar 15;11(3):e0150766. doi: 10.1371/journal.pone.0150766. eCollection 2016. |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150766 |
|
|
関連名称 |
PLOS ONE |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
甲第278号_論文(丸尾) (11.9 MB)
