@phdthesis{oai:fdc.repo.nii.ac.jp:00000145, author = {Takaesu, Yu and Suzuki, Nao and Naito, Marie and Watanabe, Takeshi and Shimazu, Atsushi and Yatabe, Naoko and Yoneda, Masahiro and Hirofuji, Takao and Hanioka, Takashi}, month = {2022-03-25, 2022-03-25, 2022-03-25}, note = {2021年度, We sought new markers to predict oral malodor. Seventy-five adults complaining of oral malodor were classified into 3 groups clinically: no oral malodor, physiologic oral malodor, and periodontitis-derived oral malodor. In addition to conventional clinical parameters, 7 salivary components, occlusal force, and lip-closing force were compared among the groups. Concerning the salivary components, cariogenic bacteria, occult blood, leukocytes, and ammonia differed significantly among the groups. Multiple logistic regression analyses indicated that tongue-coating scores and ammonia levels were significantly associated with genuine oral malodor, including physiologic oral malodor and periodontitis-derived oral malodor, and the tongue-coating score, plaque index, and occult blood level were significantly associated with periodontitis-derived oral malodor. Occlusal force and lip-closing force did not differ among the groups. However, there was a statistically significant interaction between occlusal force and lip-closing force in oral malodor in women (P = .019). Novel salivary markers, ammonia levels, and occult blood levels may predict genuine oral malodor and periodontitis-derived oral malodor, respectively. An interaction effect between occlusal force and lip-closing force on oral malodor was identified in women.}, school = {福岡歯科大学}, title = {Novel oral biomarkers predicting oral malodor.}, year = {} }